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Sierra 2500

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Used 2012 GMC Sierra 2500 SLE w/ Suspension Package, Off-Road

Used 2012 GMC Sierra 2500 SLE w/ Suspension Package, Off-Road Pleasant Hill IA 50317

Automatic

Fullsize Crew Cab

8-Cylinder Turbo

Diesel

Used 2013 GMC Sierra 2500 Denali w/ Suspension Package, Off-Road

Used 2013 GMC Sierra 2500 Denali w/ Suspension Package, Off-Road Des Moines IA 50317

Denali

All Terrain HD Package

Used 2018 GMC Sierra 2500 SLT w/ All Terrain HD Package

Used 2018 GMC Sierra 2500 SLT w/ All Terrain HD Package Des Moines IA 50317

Denali Reserve Package

Max Trailering Package

New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package

New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package Clive IA 50325

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Des Moines IA 68058

AT4 Premium Plus Package

Gooseneck/5TH Wheel Package

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Des Moines IA 50313

Denali Ultimate Package

Gooseneck/5th Wheel Prep Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package Ames IA 50010

LPO, GMC Protection Package

Used 2020 GMC Sierra 2500 Denali w/ LPO, GMC Protection Package

Used 2020 GMC Sierra 2500 Denali w/ LPO, GMC Protection Package Grinnell IA 50112

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Clive IA 50325

Snow Plow Prep/Camper Package

Gasoline

Technology Package

Used 2024 GMC Sierra 2500 Denali w/ Technology Package

Used 2024 GMC Sierra 2500 Denali w/ Technology Package Urbandale IA 50322

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package Indianola IA 50125

New 2025 GMC Sierra 2500 Denali Ultimate

New 2025 GMC Sierra 2500 Denali Ultimate Clive IA 50325

Denali Ultimate

New 2025 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package

New 2025 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package Clive IA 50325

Certified

Heavy Duty Front Spring/Camper Package

Certified 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package

Certified 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Ankeny IA 50021

Third-Party Certified

LPO, Hitch Package

Used 2024 GMC Sierra 2500 AT4X

Used 2024 GMC Sierra 2500 AT4X Ankeny IA 50021

AT4X

New 2026 GMC Sierra 2500 Denali w/ Max Trailering Package

New 2026 GMC Sierra 2500 Denali w/ Max Trailering Package Clive IA 50325

New 2026 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package

New 2026 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package Clive IA 50325

Used 2025 GMC Sierra 2500 Denali Ultimate

Used 2025 GMC Sierra 2500 Denali Ultimate Ankeny IA 50021

Certified 2024 GMC Sierra 2500 AT4X

Certified 2024 GMC Sierra 2500 AT4X Clive IA 50325

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Granger IA 50109

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Clive IA 50325

Fullsize Extended Cab

Skid Plate Package

Used 2005 GMC Sierra 2500 SLE w/ Skid Plate Package

Used 2005 GMC Sierra 2500 SLE w/ Skid Plate Package Des Moines IA 50322

AT4 Premium Package

Driver Alert Package II

Certified 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package

Certified 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package Clive IA 50325

Used 2020 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Ames IA 50010

Used 2024 GMC Sierra 2500 Denali

Used 2024 GMC Sierra 2500 Denali Waukee IA 50263

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Ankeny IA 50021

Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Clive IA 50325

Used 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package

Used 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package Des Moines IA 50313

Des Moines - Ames

Used Cars for Sale

Test drive Used GMC Sierra 2500 at home in Des Moines, IA. Search from 28 Used GMC Sierra 2500 cars for sale, including a  2005 GMC Sierra 2500 SLE, a  2005 GMC Sierra 2500 SLT, and a  2012 GMC Sierra 2500 SLE ranging in price from $12,999 to $85,495.

Used GMC Sierra 2500 for Sale in Des Moines, IA - Autotrader

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 28 GMC Sierra 2500 for sale, including a Certified 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package, a Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package, and a Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package ranging in price from $12,999 to $85,495.

Autotrader has 28 GMC Sierra 2500 for sale near Des Moines, IA, including a Certified 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package, a Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package, and a Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package ranging in price from $12,999 to $85,495.

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Used GMC Sierra 2500 for Sale in Des Moines, IA

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Certified 2024 GMC Sierra 2500 AT4X

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2012 GMC Sierra 2500

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