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Sierra 2500

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Used 2024 GMC Sierra 2500 Pro w/ Convenience Package

Used 2024 GMC Sierra 2500 Pro w/ Convenience Package Panama City FL 32405

Automatic

Fullsize Regular Cab

8-Cylinder Turbo

Diesel

Gooseneck/5th Wheel Prep Package

Used 2024 GMC Sierra 2500 Pro

Used 2024 GMC Sierra 2500 Pro Little River SC 29566

AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Charleston SC 29406

Used 2024 GMC Sierra 2500 AT4

Used 2024 GMC Sierra 2500 AT4 Columbia TN 38401

Certified

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package San Angelo TX 76901

Snow Plow Prep/Camper Package

Used 2024 GMC Sierra 2500 Denali w/ Snow Plow Prep/Camper Package

Used 2024 GMC Sierra 2500 Denali w/ Snow Plow Prep/Camper Package Randolph OH 44265

Denali

Gooseneck/5TH Wheel Package

Used 2022 GMC Sierra 2500 AT4 w/ Gooseneck/5TH Wheel Package

Used 2022 GMC Sierra 2500 AT4 w/ Gooseneck/5TH Wheel Package Stuart FL 34994

Flexible Fuel

Sierra Convenience Package

Snow Plow Prep Package

Used 2019 GMC Sierra 2500 4x4 Double Cab w/ Sierra Convenience Package

Used 2019 GMC Sierra 2500 4x4 Double Cab w/ Sierra Convenience Package Indianapolis IN 46227

4x4 Double Cab

Used 2024 GMC Sierra 2500 Pro Milton WI 53563

Technology Package

Used 2024 GMC Sierra 2500 Denali w/ Technology Package

Used 2024 GMC Sierra 2500 Denali w/ Technology Package Columbia KY 42728

Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Everett WA 98204

Driver Alert Package

Suspension Package, Off-Road

Used 2016 GMC Sierra 2500 Denali w/ Driver Alert Package

Used 2016 GMC Sierra 2500 Denali w/ Driver Alert Package Perry OK 73077

X31 Off-Road Package

Used 2022 GMC Sierra 2500 SLT w/ X31 Off-Road Package

Used 2022 GMC Sierra 2500 SLT w/ X31 Off-Road Package Temple TX 76502

Used 2002 GMC Sierra 2500 HD Regular Cab Long Bed

Off-Road Skid Plate Pkg

Used 2002 GMC Sierra 2500 SLE w/ Off-Road Skid Plate Pkg

Used 2002 GMC Sierra 2500 SLE w/ Off-Road Skid Plate Pkg Palm Desert CA 92211

Manual

Used 2020 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Mission TX 78572

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Pensacola FL 32505

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Rochester NY 14625

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Myrtle Beach SC 29577

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Bakersfield CA 93313

Used 2016 GMC Sierra 2500 SLE

Used 2016 GMC Sierra 2500 SLE Sylvania OH 43560

Used 2022 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package Chandler AZ 85248

Used 2024 GMC Sierra 2500 Pro w/ Convenience Package Chesapeake VA 23320

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Montgomery AL 36117

Used 2024 GMC Sierra 2500 Denali Ultimate

Used 2024 GMC Sierra 2500 Denali Ultimate Buford GA 30518

Denali Ultimate

Used 2024 GMC Sierra 2500 HD Crew Cab AT4X Pickup 4D 6 1/2 ft

AT4X AEV Edition

Used 2024 GMC Sierra 2500 AT4X w/ AT4X AEV Edition

Used 2024 GMC Sierra 2500 AT4X w/ AT4X AEV Edition Dripping Springs TX 78620

AT4X

Denali Reserve Package

LPO, Hitch Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Summerville SC 29483

Used 2024 GMC Sierra 2500 Denali Ultimate Fort Worth TX 76116

Used 2025 GMC Sierra 2500 HD Crew Cab AT4X Pickup 4D 6 1/2 ft

Used 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition

Used 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition Manhattan IL 60442

Used 2016 GMC Sierra 2500 HD Crew Cab SLE Pickup 4D 8 ft

Used 2016 GMC Sierra 2500 SLE Grosse Ile MI 48138

Used 2024 GMC Sierra 2500 Denali

Used 2024 GMC Sierra 2500 Denali Fort Worth TX 76116

Used 2021 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2021 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Vancouver WA 98661

Used 2022 GMC Sierra 2500 HD Crew Cab AT4 Pickup 4D 6 1/2 ft

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Murrieta CA 92562

Used 2024 GMC Sierra 2500 HD Crew Cab AT4 Pickup 4D 6 1/2 ft

Used 2024 GMC Sierra 2500 AT4 w/ Snow Plow Prep/Camper Package

Used 2024 GMC Sierra 2500 AT4 w/ Snow Plow Prep/Camper Package Pelham NH 03076

Used 2022 GMC Sierra 2500 AT4 w/ Snow Plow Prep/Camper Package

Used 2022 GMC Sierra 2500 AT4 w/ Snow Plow Prep/Camper Package Petoskey MI 49770

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Conway SC 29526

Used 2025 GMC Sierra 2500 HD Crew Cab Denali Ultimate Pickup 4D 6 1/2 ft

Used 2025 GMC Sierra 2500 Denali Ultimate

Used 2025 GMC Sierra 2500 Denali Ultimate Chapin SC 29036

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Hurst TX 76053

Used 2018 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Duramax Plus Package

Used 2018 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2018 GMC Sierra 2500 Denali w/ Duramax Plus Package Woodway TX 76712

Used 2023 GMC Sierra 2500 HD Crew Cab AT4 Pickup 4D 6 1/2 ft

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Miami FL 33137

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Used Cars for Sale

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Test drive Used GMC Sierra 2500 at home from the top dealers in your area. Search from 6573 Used GMC Sierra 2500 cars for sale, including a  2002 GMC Sierra 2500 SLE, a  2016 GMC Sierra 2500 Denali, and a  2016 GMC Sierra 2500 SLE ranging in price from $1,250 to $129,900.

Used GMC Sierra 2500 for Sale Near Me - Autotrader

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 6,573 GMC Sierra 2500 for sale, including a Used 2002 GMC Sierra 2500 SLE w/ Off-Road Skid Plate Pkg, a Used 2016 GMC Sierra 2500 SLE, and a Used 2018 GMC Sierra 2500 Denali w/ Duramax Plus Package ranging in price from $1,250 to $129,900.

Autotrader has 6,573 GMC Sierra 2500 for sale, including a Used 2002 GMC Sierra 2500 SLE w/ Off-Road Skid Plate Pkg, a Used 2016 GMC Sierra 2500 SLE, and a Used 2018 GMC Sierra 2500 Denali w/ Duramax Plus Package ranging in price from $1,250 to $129,900.

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Used GMC Sierra 2500 for Sale Near Me

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6,573 Matches Learn more about the GMC Sierra 2500

Used 2024 GMC Sierra 2500 Pro

Used 2016 GMC Sierra 2500 Denali

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