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Sierra 2500

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New 2025 GMC Sierra 2500 Denali Ultimate

New 2025 GMC Sierra 2500 Denali Ultimate Saint Louis MO 63123

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New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package

New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package Saint Louis MO 63123

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Gasoline

New 2025 GMC Sierra 2500 Pro

New 2025 GMC Sierra 2500 Pro Saint Louis MO 63123

AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Saint Louis MO 63123

New 2025 GMC Sierra 2500 AT4X

New 2025 GMC Sierra 2500 AT4X Saint Louis MO 63123

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New 2025 GMC Sierra 2500 SLT w/ SLT Convenience Package

New 2025 GMC Sierra 2500 SLT w/ SLT Convenience Package Collinsville IL 62234

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Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Hazelwood MO 63042

LPO, GMC Protection Package

Used 2022 GMC Sierra 2500 Denali

Used 2022 GMC Sierra 2500 Denali St. Charles MO 63303

SLT Premium Package

X31 Off-Road and Protection Package

Used 2022 GMC Sierra 2500 SLT w/ SLT Premium Package

Used 2022 GMC Sierra 2500 SLT w/ SLT Premium Package Herculaneum MO 63048

Denali Black Diamond Edition

Used 2022 GMC Sierra 2500 Denali w/ Denali Black Diamond Edition

Used 2022 GMC Sierra 2500 Denali w/ Denali Black Diamond Edition Columbia IL 62236

Driver Alert Package I

Used 2022 GMC Sierra 2500 AT4 w/ Driver Alert Package I

Used 2022 GMC Sierra 2500 AT4 w/ Driver Alert Package I Troy MO 63379

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package St. Charles MO 63303

Used 2020 GMC Sierra 2500 SLT

Used 2020 GMC Sierra 2500 SLT Florissant MO 63033

Certified

LPO, Hitch Package

Certified 2023 GMC Sierra 2500 Denali

Certified 2023 GMC Sierra 2500 Denali Collinsville IL 62234

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Ellisville MO 63011

Midsize

Sport Utility

4-Cylinder Turbo

Terrain

Tech Package

License Plate Front Mounting Package

Used 2022 GMC Terrain SLT w/ Tech Package

Used 2022 GMC Terrain SLT w/ Tech Package Saint Louis MO 63123

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Collinsville IL 62234

Flexible Fuel

Used 2016 GMC Sierra 2500 Denali

Used 2016 GMC Sierra 2500 Denali Collinsville IL 62234

X31 Off-Road Package

Used 2021 GMC Sierra 2500 SLT w/ X31 Off-Road Package

Used 2021 GMC Sierra 2500 SLT w/ X31 Off-Road Package Collinsville IL 62234

Driver Alert Package II

Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package

Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package Collinsville IL 62234

Certified 2025 GMC Sierra 2500 SLT w/ SLT Premium Package

Certified 2025 GMC Sierra 2500 SLT w/ SLT Premium Package Collinsville IL 62234

Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Collinsville IL 62234

Certified 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Certified 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package Collinsville IL 62234

HD SLE Gas Preferred Plus Package

Snow Plow Prep Package

Suspension Package, Off-Road

Used 2019 GMC Sierra 2500 SLE

Used 2019 GMC Sierra 2500 SLE Collinsville IL 62234

Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Collinsville IL 62234

LPO, Cargo Convenience Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Collinsville IL 62234

Duramax Plus Package

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package Collinsville IL 62234

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Collinsville IL 62234

SLE Convenience Package

Remote Start Package

Heated Package

Used 2024 GMC Sierra 2500 SLE w/ SLE Convenience Package

Used 2024 GMC Sierra 2500 SLE w/ SLE Convenience Package Collinsville IL 62234

Used 2024 GMC Sierra 2500 HD Crew Cab Denali Ultimate Pickup 4D 6 1/2 ft

Used 2024 GMC Sierra 2500 Denali Ultimate

Used 2024 GMC Sierra 2500 Denali Ultimate O Fallon MO 63366

Used 2022 GMC Sierra 2500 Denali Collinsville IL 62234

SLT Preferred Package

LPO, Assist Step and Floor Liner Package

Used 2021 GMC Sierra 2500 SLT w/ SLT Preferred Package

Used 2021 GMC Sierra 2500 SLT w/ SLT Preferred Package Collinsville IL 62234

New 2026 GMC Sierra 2500 Denali

New 2026 GMC Sierra 2500 Denali Highland IL 62249

Gooseneck/5TH Wheel Prep Package

LAURA BUICK GMC

Behlmann Buick GMC

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Bommarito West County

Steve Schmitt, Inc.

St Louis

Used Cars for Sale

Test drive Used GMC Sierra 2500 at home in Saint Louis, MO. Search from 106 Used GMC Sierra 2500 cars for sale, including a  2015 GMC Sierra 2500 Denali, a  2016 GMC Sierra 2500 Denali, and a  2019 GMC Sierra 2500 Denali ranging in price from $16,977 to $91,960.

Used GMC Sierra 2500 for Sale in Saint Louis, MO - Autotrader

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 106 GMC Sierra 2500 for sale, including a Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package, a Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package, and a Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package ranging in price from $16,977 to $91,960.

Autotrader has 106 GMC Sierra 2500 for sale near Saint Louis, MO, including a Certified 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package, a Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package, and a Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package ranging in price from $16,977 to $91,960.

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Used GMC Sierra 2500 for Sale in Saint Louis, MO

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