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Sierra 2500

1SA Pro Safety Plus Package

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New 2024 GMC Sierra 2500 Pro w/ 1SA Pro Safety Plus Package

New 2024 GMC Sierra 2500 Pro w/ 1SA Pro Safety Plus Package Tustin CA 92782

Automatic

New 2025 GMC Sierra 2500 Pro w/ 1SA Pro Safety Plus Package

New 2025 GMC Sierra 2500 Pro w/ 1SA Pro Safety Plus Package Tustin CA 92782

Fullsize Crew Cab

AWD4WD

Denali Reserve Package

New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package

New 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package Tustin CA 92782

Denali

8-Cylinder Turbo

Diesel

Max Trailering Package

Fullsize Extended Cab

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Used 2004 GMC Sierra 2500 SLE

Used 2004 GMC Sierra 2500 SLE Vista CA 92084

Denali Ultimate Package

Gooseneck/5th Wheel Prep Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package National City CA 91950

Used 2022 GMC Sierra 2500 HD Regular Cab SLE Pickup 2D 8 ft

SLE Convenience Package

Driver Alert Package I

Used 2022 GMC Sierra 2500 SLE w/ SLE Convenience Package

Used 2022 GMC Sierra 2500 SLE w/ SLE Convenience Package Oceanside CA 92057

SLT Premium Plus Package

Technology Package

Gooseneck/5TH Wheel Package

X31 Off-Road Package

Used 2020 GMC Sierra 2500 SLT w/ SLT Premium Plus Package

Used 2020 GMC Sierra 2500 SLT w/ SLT Premium Plus Package National City CA 91950

Used 2007 GMC Sierra 2500 HD Crew Cab SLT Pickup 4D 6 1/2 ft

Z71 Off-Road Package

EZ-Lift Tailgate Package

Used 2007 GMC Sierra 2500 SLT w/ Z71 Off-Road Package

Used 2007 GMC Sierra 2500 SLT w/ Z71 Off-Road Package Alpine CA 91901

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package Escondido CA 92029

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Tustin CA 92782

Used 2021 GMC Sierra 2500 Denali w/ Technology Package

Used 2021 GMC Sierra 2500 Denali w/ Technology Package Carlsbad CA 92008

SLE Value Package;

Sierra HD Pro Safety Plus Package

New 2026 GMC Sierra 2500 SLE w/ SLE Value Package;

New 2026 GMC Sierra 2500 SLE w/ SLE Value Package; Tustin CA 92782

Used 2025 GMC Sierra 2500 Denali Ultimate

Used 2025 GMC Sierra 2500 Denali Ultimate Escondido CA 92029

Denali Ultimate

AT4 Premium Plus Package

LPO, Cargo Convenience Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Escondido CA 92029

New 2026 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

New 2026 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Tustin CA 92782

Used 2024 GMC Sierra 2500 SLE w/ SLE Value Package;

Used 2024 GMC Sierra 2500 SLE w/ SLE Value Package; El Cajon CA 92021

Duramax Plus Package

Used 2015 GMC Sierra 2500 SLT w/ Duramax Plus Package

Used 2015 GMC Sierra 2500 SLT w/ Duramax Plus Package Escondido CA 92029

Preferred Package

Certified

LPO, Hitch Package

Certified 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package San Diego CA 92108

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Tustin CA 92782

Used 2023 GMC Sierra 2500 SLE w/ SLE Convenience Package

Used 2023 GMC Sierra 2500 SLE w/ SLE Convenience Package Poway CA 92064

Flexible Fuel

Used 2016 GMC Sierra 2500 HD Crew Cab SLE Pickup 4D 8 ft

SLE Preferred Package

Used 2016 GMC Sierra 2500 SLE w/ SLE Preferred Package

Used 2016 GMC Sierra 2500 SLE w/ SLE Preferred Package Carlsbad CA 92008

Used 2015 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Suspension Package, Off-Road

Used 2015 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2015 GMC Sierra 2500 Denali w/ Duramax Plus Package Chula Vista CA 91913

New 2026 GMC Sierra 2500 Pro

New 2026 GMC Sierra 2500 Pro National City CA 91950

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San Diego

Used Cars for Sale

Test drive Used GMC Sierra 2500 at home in San Diego, CA. Search from 15 Used GMC Sierra 2500 cars for sale, including a  2004 GMC Sierra 2500 SLE, a  2007 GMC Sierra 2500 SLT, and a  2015 GMC Sierra 2500 Denali ranging in price from $9,995 to $91,236.

Used GMC Sierra 2500 for Sale in San Diego, CA - Autotrader

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 15 GMC Sierra 2500 for sale, including a Certified 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, a Used 2004 GMC Sierra 2500 SLE, and a Used 2007 GMC Sierra 2500 SLT w/ Z71 Off-Road Package ranging in price from $9,995 to $91,236.

Autotrader has 15 GMC Sierra 2500 for sale near San Diego, CA, including a Certified 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, a Used 2004 GMC Sierra 2500 SLE, and a Used 2007 GMC Sierra 2500 SLT w/ Z71 Off-Road Package ranging in price from $9,995 to $91,236.

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Used GMC Sierra 2500 for Sale in San Diego, CA

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Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

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