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New 2025 GMC Sierra 2500 Pro w/ Convenience Package

New 2025 GMC Sierra 2500 Pro w/ Convenience Package Healdsburg CA 95448

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New 2025 GMC Sierra 2500 Pro

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New 2025 GMC Sierra 2500 Denali Ultimate

New 2025 GMC Sierra 2500 Denali Ultimate Healdsburg CA 95448

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New 2025 GMC Sierra 2500 SLT w/ SLT Convenience Package

New 2025 GMC Sierra 2500 SLT w/ SLT Convenience Package Healdsburg CA 95448

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Used 2024 GMC Sierra 2500 Denali Ultimate

Used 2024 GMC Sierra 2500 Denali Ultimate Jamestown CA 95327

Duramax Plus Package

Gooseneck/5TH Wheel Prep Package

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package Galt CA 94118

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Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package Healdsburg CA 95448

Denali Reserve Package

Max Trailering Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Pleasanton CA 94588

AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Healdsburg CA 95448

Denali Ultimate Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package Pleasanton CA 94588

Used 2015 GMC Sierra 2500 SLE

Used 2015 GMC Sierra 2500 SLE Vacaville CA 95687

Gooseneck/5TH Wheel Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Concord CA 94520

X31 Off-Road Package

Used 2020 GMC Sierra 2500 SLT w/ X31 Off-Road Package

Used 2020 GMC Sierra 2500 SLT w/ X31 Off-Road Package Concord CA 94520

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Santa Clara CA 95051

Denali Black Diamond Edition

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Heavy Duty Front Spring/Camper Package

Used 2022 GMC Sierra 2500 Denali w/ Denali Black Diamond Edition

Used 2022 GMC Sierra 2500 Denali w/ Denali Black Diamond Edition San Francisco CA 94112

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package Concord CA 94520

Fullsize Extended Cab

Skid Plate Package

Used 2006 GMC Sierra 2500 SLE w/ Skid Plate Package

Used 2006 GMC Sierra 2500 SLE w/ Skid Plate Package Walnut Creek CA 94596

Used 2022 GMC Sierra 2500 AT4

Used 2022 GMC Sierra 2500 AT4 Rio Vista CA 94571

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package San Jose CA 95117

AT4 Premium Package

Used 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package

Used 2020 GMC Sierra 2500 AT4 w/ AT4 Premium Package San Francisco CA 94112

Snow Plow Prep/Camper Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Walnut Creek CA 94507

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Galt CA 94118

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Healdsburg CA 95448

AT4X AEV Edition

New 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition

New 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition Healdsburg CA 95448

AT4X

Used 2023 GMC Sierra 2500 Denali

Used 2023 GMC Sierra 2500 Denali Concord CA 94520

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package Pleasanton CA 94588

Suspension Package, Off-Road

Used 2017 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2017 GMC Sierra 2500 Denali w/ Duramax Plus Package San Jose CA 95136

Used 2021 GMC Sierra 2500 SLT w/ SLT Convenience Package

Used 2021 GMC Sierra 2500 SLT w/ SLT Convenience Package Brentwood CA 94513

Used 2024 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package

Used 2024 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package San Jose CA 95136

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package San Francisco CA 94103

Used 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition

Used 2025 GMC Sierra 2500 AT4X w/ AT4X AEV Edition San Jose CA 95136

Used 2024 GMC Sierra 2500 Pro w/ Convenience Package

Used 2024 GMC Sierra 2500 Pro w/ Convenience Package Dublin CA 94568

Used 2023 GMC Sierra 2500 SLE

Used 2023 GMC Sierra 2500 SLE Galt CA 94118

Technology Package

Used 2023 GMC Sierra 2500 Denali w/ Technology Package

Used 2023 GMC Sierra 2500 Denali w/ Technology Package Concord CA 94520

Used 2020 GMC Sierra 2500 HD Crew Cab Denali Pickup 4D 6 1/2 ft

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Vacaville CA 95688

San Francisco - Oak - San Jose

Used Cars for Sale

Test drive Used GMC Sierra 2500 at home in San Francisco, CA. Search from 34 Used GMC Sierra 2500 cars for sale, including a  2006 GMC Sierra 2500 SLE, a  2015 GMC Sierra 2500 SLE, and a  2017 GMC Sierra 2500 Denali ranging in price from $18,507 to $90,999.

Used GMC Sierra 2500 for Sale in San Francisco, CA - Autotrader

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 34 GMC Sierra 2500 for sale, including a Used 2006 GMC Sierra 2500 SLE w/ Skid Plate Package, a Used 2015 GMC Sierra 2500 SLE, and a Used 2017 GMC Sierra 2500 Denali w/ Duramax Plus Package ranging in price from $18,507 to $90,999.

Autotrader has 34 GMC Sierra 2500 for sale near San Francisco, CA, including a Used 2006 GMC Sierra 2500 SLE w/ Skid Plate Package, a Used 2015 GMC Sierra 2500 SLE, and a Used 2017 GMC Sierra 2500 Denali w/ Duramax Plus Package ranging in price from $18,507 to $90,999.

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Used GMC Sierra 2500 for Sale in San Francisco, CA

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Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package

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Used 2006 GMC Sierra 2500 SLE

Used 2020 GMC Sierra 2500 SLT

Used 2021 GMC Sierra 2500 Denali