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Used Cars for SaleGMCSierra 2500

Used GMC Sierra 2500 for Sale in O Fallon, MO

63366

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GMC

Models

Sierra 2500

Acadia (167)

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Hummer EV (1)

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GMC

Models

Sierra 2500

Acadia (167)

Caballero

Canyon (44)

Envoy

Envoy XL

Envoy XUV

G1500

G2500

G3500

Hummer EV (1)

Jimmy (1)

Other GMC Models

S15 Jimmy

S15 Pickup

Safari

Savana 1500

Savana 2500 (15)

Savana 3500 (1)

Savana 4500

Sierra 1500 (404)

Sierra 2500 (123)

Sierra 3500 (34)

Sierra EV (1)

Sonoma (1)

Suburban

Syclone

Terrain (138)

TopKick C4500

TopKick C5500

Typhoon

Yukon (107)

Yukon XL (66)

Sierra 2500 Trims

Any

AT4 (28)

AT4X (8)

Classic SL

Classic SLE

Classic SLT

Classic W/T

Denali (46)

Denali Ultimate (12)

Pro (2)

SL

SLE (10)

SLT (12)

W/T (3)

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Used (123)

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Certified Program

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New (267)

Used (123)

Manufacturer Certified (28)

Third-Party Certified (1)

Certified Program

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Crew Cab (81)

Extended Cab (5)

Regular Cab (3)

Crew Cab (81)

Extended Cab (5)

Regular Cab (3)

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Long (10)

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Short (0)

Medium (110)

Long (10)

Include unspecified lengths (0)

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It looks like this GMC Sierra 2500 has already found a new home.

Check out other great options we've picked for you.

Sponsored by O'Fallon Buick GMC

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Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

69,500

O'Fallon Buick GMC

45View Vehicles

123 Matches

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Certified 2024 GMC Sierra 2500 SLE w/ SLE Convenience Package

CarBravo Certified

2024 GMC Sierra 2500

SLE
17K mi

50,952

See payment

Good PriceNo Accidents

Sponsored by Sapaugh GM Country

42.3 mi. away

Online Paperwork

Used 2022 GMC Sierra 2500 SLT w/ SLT Convenience Package

Used

2022 GMC Sierra 2500

SLT
37K mi

54,700

See payment

Great PriceNo Accidents

Sponsored by Clement Supercenter

8.79 mi. away

Used 2025 GMC Sierra 2500 Denali w/ Denali Reserve Package

Used

2025 GMC Sierra 2500

Denali
30K mi

67,500

See payment

Sponsored by Clement Supercenter

8.79 mi. away

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and Within Budget

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Based on 4.5% APR for mos.Update Settings

Used 2022 GMC Sierra 2500 SLT w/ SLT Convenience Package

Used

2022 GMC Sierra 2500

SLT
37K mi

54,700

See payment

Great PriceNo Accidents

Clement Supercenter

8.79 mi. away

Used 2024 GMC Sierra 2500 Denali Ultimate

Used

2024 GMC Sierra 2500

Denali Ultimate
6K mi

91,960

See payment

Private Seller Exchange

Buy Online. Clean title. No Hassle

New 2026 GMC Sierra 2500 SLE w/ SLE Value Package;

Consider New, Similar Payment

2026 GMC Sierra 2500

SLE
7 mi

68,962

See details

LAURA BUICK GMC

38.98 mi. away

Online Paperwork
Delivery

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Used 2025 GMC Sierra 2500 SLE w/ SLE Value Package;

Used

2025 GMC Sierra 2500

SLE
6K mi

52,900

See payment

Great PriceNo Accidents

Behlmann Buick GMC

18.42 mi. away

Online Paperwork

Item 1 of 10.

How many passenger seats do you need in your truck?

Do you want

Adaptive Cruise Control?

Automatically adjusts your speed to maintain a safe distance from the car ahead.

Do you want

Backup Camera?

See behind your vehicle while reversing with a live video feed to avoid obstacles.

Do you want

Bluetooth, Hands-Free?

Make and receive calls safely through your car's audio system without touching your phone.

Do you want

Cross Traffic Alert?

Warns you of approaching vehicles from the sides when backing out of a parking spot.

Do you want

Keyless Start?

Start your car with the push of a button while the key fob stays in your pocket or bag.

Do you want

Lane Departure Warning?

Alerts you if your car begins to drift out of its lane without signaling.

Do you want

Premium Audio?

Enjoy high-quality sound with advanced speakers for a better listening experience.

Do you want

Remote Engine Start?

Start your car from a distance to preheat or cool the cabin before you get in.

Do you want

Security System?

Alerts you with a loud alarm if someone tries to break into your vehicle.

Sponsored

Used 2021 GMC Sierra 2500 4WD Crew Cab w/ Convenience Package

Used 2021 GMC Sierra 2500 4WD Crew Cab w/ Convenience Package

Used 2021 GMC Sierra 2500 4WD Crew Cab w/ Convenience Package

Used 2021 GMC Sierra 2500 4WD Crew Cab w/ Convenience Package

Used

2021 GMC Sierra 2500

4WD Crew Cab
38K mi

40,985

See payment

Great PriceNo Accidents

Used 2023 GMC Sierra 2500 Denali

Ford Blue Certified

2023 GMC Sierra 2500

Denali
27K mi

59,412

See payment

Great Price

Weber Ford

31.3 mi. away

Online Paperwork

Used 2024 GMC Sierra 2500 SLT w/ SLT Premium Package

Used

2024 GMC Sierra 2500

SLT
20K mi

60,800

See payment

Great PriceNo Accidents

Bommarito West County

16.78 mi. away

Online Paperwork

Used 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2025 GMC Sierra 2500

AT4
12K mi

76,800

See payment

Good PriceNo Accidents

Clement Supercenter

8.79 mi. away

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Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2021 GMC Sierra 2500

Denali
69K mi

57,490

See payment

Good PriceNo Accidents

Jim Trenary Chevrolet Of Troy

17.13 mi. away

Online Paperwork

Used 2020 GMC Sierra 2500 SLT

Used

2020 GMC Sierra 2500

SLT
46K mi

48,800

See payment

Great PriceNo Accidents

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2020 GMC Sierra 2500

Denali
77K mi

51,991

See payment

Great PriceNo Accidents

Dave Sinclair Buick GMC

27.87 mi. away

Online Paperwork

Used 2020 GMC Sierra 2500 SLT w/ SLT Premium Plus Package

Used

2020 GMC Sierra 2500

SLT
54K mi

47,900

See payment

Great PriceNo Accidents

Behlmann Buick GMC

18.42 mi. away

Online Paperwork

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Used 2016 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used

2016 GMC Sierra 2500

Denali
120K mi

37,990

See payment

Good Price

Poage Chevrolet

8.06 mi. away

Used 2023 GMC Sierra 2500 SLT w/ SLT Premium Package

Used

2023 GMC Sierra 2500

SLT
63K mi

51,800

See payment

Great PriceNo Accidents

Clement Supercenter

8.79 mi. away

Used 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2024 GMC Sierra 2500

AT4
36K mi

68,300

See payment

Great PriceNo Accidents

Clement Supercenter

8.79 mi. away

Used 2024 GMC Sierra 2500 AT4 w/ Technology Package

Used

2024 GMC Sierra 2500

AT4
34K mi

69,700

See payment

Great PriceNo Accidents

Clement Supercenter

8.79 mi. away

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2023 GMC Sierra 2500

AT4
39K mi

57,600

See payment

Great PriceNo Accidents

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2023 GMC Sierra 2500

Denali
31K mi

61,300

See payment

Great PriceNo Accidents

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Certified 2025 GMC Sierra 2500 Denali Ultimate

Certified

2025 GMC Sierra 2500

Denali Ultimate
7K mi

84,995

See payment

Great PriceNo Accidents

Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

Used 2025 GMC Sierra 2500 AT4X

Used

2025 GMC Sierra 2500

AT4X
12K mi

83,950

See payment

Great PriceNo Accidents

Dean Team of Kirkwood

22.6 mi. away

Used 2024 GMC Sierra 2500 AT4

Used

2024 GMC Sierra 2500

AT4
46K mi

67,900

See payment

Great PriceNo Accidents

Behlmann Buick GMC

18.42 mi. away

Online Paperwork

Used 2015 GMC Sierra 2500 2WD Regular Cab

Used

2015 GMC Sierra 2500

2WD Regular Cab
116K mi

17,500

See payment

Private Seller Exchange

20.88 mi. away

Buy Online. Clean title. No Hassle

Used 2020 GMC Sierra 2500 Denali

Used

2020 GMC Sierra 2500

Denali
37K mi

59,399

See payment

Great PriceNo Accidents

AutoCenters Nissan

41.95 mi. away

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2023 GMC Sierra 2500

Denali
28K mi

64,897

See payment

Great PriceNo Accidents

AutoCenters Nissan

41.95 mi. away

Used 2025 GMC Sierra 2500 SLT w/ SLT Convenience Package

Used

2025 GMC Sierra 2500

SLT
7K mi

71,380

See payment

Great PriceNo Accidents

AutoCenters Nissan

41.95 mi. away

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