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Used Cars for SaleGMCSierra 2500

Used GMC Sierra 2500 for Sale in O Fallon, MO

63366

|Filters (3)

Purchase Online(3)

GMC Certified Pre-Owned(40)

2014 and newer(121)

Rear Wheel Drive(3)

Black(34)

Red(9)

2009 and older(2)

AWD/4WD(118)

Blue(2)

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Sierra 2500

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Terrain (147)

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AT4 (33)

AT4X (1)

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Denali (37)

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SLT (19)

W/T (1)

Condition (1 selected)

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Used (123)

Manufacturer Certified (40)

Third-Party Certified (1)

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Great Price (67)

Ways to Purchase

Mileage

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Sponsored by O'Fallon Buick GMC

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Price Drop360°

Used 2024 GMC Sierra 2500 SLT w/ SLT Premium Package

Used 2024 GMC Sierra 2500 SLT w/ SLT Premium Package

61,900

Good Price

O'Fallon Buick GMC

7View Vehicles

123 Matches

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Used 2017 GMC Sierra 2500 SLT

Used

2017 GMC Sierra 2500

SLT
152K mi

25,995

Good Price

Sponsored by Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified

2024 GMC Sierra 2500

AT4
49K mi

66,995

Great Price

Sponsored by Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

Newly Listed

Used 2018 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used

2018 GMC Sierra 2500

Denali
128K mi

41,995

Good Price

Sponsored by Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

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Monthly Payment

Down Payment

Get My Kelley Blue Book® Car Value

$

Based on 4.5% APR for mos.Update Settings

Used 2024 GMC Sierra 2500 SLE w/ SLE Convenience Package

Used

2024 GMC Sierra 2500

SLE
7K mi

60,000

See payment

Great Price

Clement Supercenter

8.79 mi. away

Used 2024 GMC Sierra 2500 Denali Ultimate

Used

2024 GMC Sierra 2500

Denali Ultimate
6K mi

91,960

See payment

Private Seller Exchange

Buy Online. Clean title. No Hassle

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New 2026 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Consider New, Similar Payment

2026 GMC Sierra 2500

AT4
7 mi

83,832

LAURA BUICK GMC

38.98 mi. away

Online Paperwork
Delivery

Price Drop

Used 2024 GMC Sierra 2500 SLT w/ SLT Premium Package

Used

2024 GMC Sierra 2500

SLT
25K mi

61,900

Good Price

O'Fallon Buick GMC

4.76 mi. away

Online Paperwork

Item 1 of 10.

How many passenger seats do you need in your truck?

Do you want

Adaptive Cruise Control?

Automatically adjusts your speed to maintain a safe distance from the car ahead.

Do you want

Backup Camera?

See behind your vehicle while reversing with a live video feed to avoid obstacles.

Do you want

Bluetooth, Hands-Free?

Make and receive calls safely through your car's audio system without touching your phone.

Do you want

Cross Traffic Alert?

Warns you of approaching vehicles from the sides when backing out of a parking spot.

Do you want

Keyless Start?

Start your car with the push of a button while the key fob stays in your pocket or bag.

Do you want

Lane Departure Warning?

Alerts you if your car begins to drift out of its lane without signaling.

Do you want

Premium Audio?

Enjoy high-quality sound with advanced speakers for a better listening experience.

Do you want

Remote Engine Start?

Start your car from a distance to preheat or cool the cabin before you get in.

Do you want

Security System?

Alerts you with a loud alarm if someone tries to break into your vehicle.

Used 2022 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Ford Blue Certified

2022 GMC Sierra 2500

Denali
12K mi

69,500

Great Price

Weber Ford

31.3 mi. away

Online Paperwork

Sponsored

Used 2017 GMC Sierra 2500 SLT

Used

2017 GMC Sierra 2500

SLT
136K mi

29,000

Good Price

Used 2017 GMC Sierra 2500 2WD Regular Cab w/ Sierra Convenience Package

Used

2017 GMC Sierra 2500

2WD Regular Cab
113K mi

17,995

See payment

Great Price

STLCarZ

8.56 mi. away

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2023 GMC Sierra 2500

AT4
119K mi

50,700

Good Price

O'Fallon Buick GMC

4.76 mi. away

Online Paperwork

Price Drop

Used 2023 GMC Sierra 2500 SLT w/ SLT Premium Package

Used

2023 GMC Sierra 2500

SLT
63K mi

53,000

See payment

Great Price

Clement Supercenter

8.79 mi. away

Price Drop

Used 2020 GMC Sierra 2500 SLT

Used

2020 GMC Sierra 2500

SLT
46K mi

51,343

See payment

Great Price

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

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Price Drop

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2020 GMC Sierra 2500

Denali
36K mi

58,606

See payment

Great Price

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2023 GMC Sierra 2500

AT4
46K mi

64,880

See payment

Great Price

Johnny Londoff Autoplex

2.97 mi. away

Newly Listed

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used

2019 GMC Sierra 2500

Denali
85K mi

49,995

Great Price

Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

Newly Listed

Used 2006 GMC Sierra 2500 W/T w/ Skid Plate Package

Used

2006 GMC Sierra 2500

W/T
137K mi

32,000

See payment

Private Seller Exchange

45.66 mi. away

Buy Online. Clean title. No Hassle

Price Drop

Used 2015 GMC Sierra 2500 2WD Regular Cab

Used

2015 GMC Sierra 2500

2WD Regular Cab
116K mi

17,500

See payment

Private Seller Exchange

20.88 mi. away

Buy Online. Clean title. No Hassle

Used 2021 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2021 GMC Sierra 2500

Denali
45K mi

60,271

See payment

Good Price

Frank Leta Honda

6.37 mi. away

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Newly Listed

Used 2021 GMC Sierra 2500 SLE w/ SLE Convenience Package

Used

2021 GMC Sierra 2500

SLE
57K mi

46,998

See payment

Great Price

AutoCenters Nissan

41.95 mi. away

Used 2025 GMC Sierra 2500 Denali Ultimate w/ Max Trailering Package

Used

2025 GMC Sierra 2500

Denali Ultimate
797 mi

89,000

See payment

Suntrup Buick GMC

7.51 mi. away

Price Drop

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used

2020 GMC Sierra 2500

Denali
91K mi

49,000

Great Price

Bommarito West County

16.78 mi. away

Online Paperwork

Used 2021 GMC Sierra 2500 SLE w/ SLE Value Package;

Used

2021 GMC Sierra 2500

SLE
52K mi

48,000

See payment

Great Price

Clement Supercenter

8.79 mi. away

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Price Drop

Used 2023 GMC Sierra 2500 SLE w/ Gooseneck/5TH Wheel Package

Used

2023 GMC Sierra 2500

SLE
22K mi

53,500

See payment

Great Price

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Price Drop

Used 2022 GMC Sierra 2500 Denali w/ LPO, GMC Protection Package

Used

2022 GMC Sierra 2500

Denali
44K mi

60,100

See payment

Great Price

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Price Drop

Used 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used

2022 GMC Sierra 2500

AT4
32K mi

62,500

See payment

Great Price

Clement Chrysler Dodge Jeep Ram Florissant

21.78 mi. away

Certified 2024 GMC Sierra 2500 Denali Ultimate

Certified

2024 GMC Sierra 2500

Denali Ultimate
5K mi

80,995

Great Price

Laura Buick GMC, Inc.

38.98 mi. away

Online Paperwork
Delivery

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