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Spider

Fullsize Regular Cab

Truck

AWD4WD

8-Cylinder Turbo

Diesel

Used

Sierra 2500

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Used 2022 GMC Sierra 2500 SLE

Used 2022 GMC Sierra 2500 SLE Herculaneum MO 63048

Automatic

8-Cylinder

Gasoline

Sierra 1500

Pro Value Package

Snow Plow Prep Package

New 2025 GMC Sierra 1500 Pro w/ Pro Value Package

New 2025 GMC Sierra 1500 Pro w/ Pro Value Package O Fallon MO 63368

Compact Crew Cab

4-Cylinder Turbo

Canyon

Convenience Package

Preferred Package

New 2025 GMC Canyon Elevation w/ Convenience Package

New 2025 GMC Canyon Elevation w/ Convenience Package O Fallon MO 63368

Elevation

Fullsize

Sport Utility

Acadia

New 2025 GMC Acadia Elevation

New 2025 GMC Acadia Elevation O Fallon MO 63368

Fullsize Crew Cab

AT4 Premium Plus Package

Gooseneck/5th Wheel Prep Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Highland IL 62249

AT4 Preferred Package

Driver Alert Package I

Gooseneck/5TH Wheel Package

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Preferred Package

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Preferred Package St. Charles MO 63303

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Saint Peters MO 63376

New 2025 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Collinsville IL 62234

Used 2023 GMC Sierra 2500 Pro w/ Convenience Package

Used 2023 GMC Sierra 2500 Pro w/ Convenience Package Herculaneum MO 63048

LPO, GMC Protection Package

Heavy Duty Front Spring/Camper Package

Used 2024 GMC Sierra 2500 Denali Ultimate

Used 2024 GMC Sierra 2500 Denali Ultimate St. Charles MO 63303

Denali Ultimate

Electric

Sierra EV

New 2026 GMC Sierra EV Elevation

New 2026 GMC Sierra EV Elevation O Fallon MO 63368

Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Hazelwood MO 63042

Denali

Hummer EV

New 2025 GMC Hummer EV 3X

New 2025 GMC Hummer EV 3X O Fallon MO 63368

Used 2022 GMC Sierra 2500 Denali

Used 2022 GMC Sierra 2500 Denali St. Charles MO 63303

Denali Reserve Package

Max Trailering Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package

Used 2024 GMC Sierra 2500 Denali w/ Denali Reserve Package O Fallon MO 63368

SLT Premium Package

X31 Off-Road and Protection Package

Snow Plow Prep/Camper Package

Used 2022 GMC Sierra 2500 SLT w/ SLT Premium Package

Used 2022 GMC Sierra 2500 SLT w/ SLT Premium Package Herculaneum MO 63048

Flexible Fuel

Suspension Package, Off-Road

Used 2018 GMC Sierra 2500 Denali w/ Suspension Package, Off-Road

Used 2018 GMC Sierra 2500 Denali w/ Suspension Package, Off-Road O'fallon MO 63368

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package

Used 2023 GMC Sierra 2500 Denali w/ Denali Ultimate Package St. Charles MO 63303

Driver Alert Package II

Used 2022 GMC Sierra 2500 SLT w/ SLT Premium Package Troy MO 63379

Used 2020 GMC Sierra 2500 SLT

Used 2020 GMC Sierra 2500 SLT Florissant MO 63033

Used 2024 GMC Sierra 1500 AT4X

Used 2024 GMC Sierra 1500 AT4X O Fallon MO 63368

AT4X

Used 2023 GMC Sierra 2500 Denali

Used 2023 GMC Sierra 2500 Denali Saint Louis MO 63132

Yukon XL

Used 2019 GMC Yukon XL Denali

Used 2019 GMC Yukon XL Denali O Fallon MO 63368

Certified

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Collinsville IL 62234

AT4X AEV Edition

Certified 2024 GMC Sierra 2500 AT4X w/ AT4X AEV Edition

Certified 2024 GMC Sierra 2500 AT4X w/ AT4X AEV Edition Collinsville IL 62234

Graphite Edition

X31 Off-Road Package

Used 2024 GMC Sierra 1500 Pro w/ Graphite Edition

Used 2024 GMC Sierra 1500 Pro w/ Graphite Edition O Fallon MO 63368

Used 2016 GMC Sierra 2500 Denali

Used 2016 GMC Sierra 2500 Denali Collinsville IL 62234

6-Cylinder

Used 2013 GMC Acadia SLT

Used 2013 GMC Acadia SLT O Fallon MO 63368

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Preferred Package O Fallon MO 63368

Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package

Certified 2021 GMC Sierra 2500 SLT w/ SLT Premium Package Collinsville IL 62234

Used 2023 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package St. Charles MO 63303

Technology Package

Used 2020 GMC Sierra 2500 AT4 w/ Technology Package

Used 2020 GMC Sierra 2500 AT4 w/ Technology Package Ellisville MO 63011

HD SLE Gas Preferred Plus Package

Used 2019 GMC Sierra 2500 SLE

Used 2019 GMC Sierra 2500 SLE Collinsville IL 62234

Duramax Plus Package

Used 2016 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2016 GMC Sierra 2500 Denali w/ Duramax Plus Package Troy MO 63379

2500HD SLT Gas Premium Plus Package

Used 2018 GMC Sierra 2500 SLT

Used 2018 GMC Sierra 2500 SLT Collinsville IL 62234

LPO, Hitch Package

Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package

Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package Collinsville IL 62234

Midsize

4-Cylinder

Terrain

Used 2015 GMC Terrain Denali

Used 2015 GMC Terrain Denali O Fallon MO 63368

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package

Used 2019 GMC Sierra 2500 Denali w/ Duramax Plus Package Collinsville IL 62234

Used 2020 GMC Sierra 2500 Denali w/ Denali Ultimate Package Collinsville IL 62234

Used 2020 GMC Sierra 1500 Denali

Used 2020 GMC Sierra 1500 Denali O Fallon MO 63368

Used 2024 GMC Sierra 2500 HD Crew Cab Denali Ultimate Pickup 4D 6 1/2 ft

Used 2024 GMC Sierra 2500 Denali Ultimate O Fallon MO 63366

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Steve Schmitt, Inc.

St Louis

Used Cars for Sale

Test drive Used GMC Sierra 2500 at home in O Fallon, MO. Search from 110 Used GMC Sierra 2500 cars for sale, including a  2016 GMC Sierra 2500 Denali, a  2018 GMC Sierra 2500 Denali, and a  2018 GMC Sierra 2500 SLT ranging in price from $16,977 to $91,960.

Used GMC Sierra 2500 for Sale in O Fallon, MO - Autotrader

The GMC Sierra 2500 is an intriguing mix of heavy-hitting workhorse and glitzy luxury. With powerful <a href="https://www.autotrader.com/cars-for-sale/diesel/gmc/sierra-2500" target="_blank">diesel</a> or <a href="https://www.autotrader.com/cars-for-sale/gasoline/gmc/sierra-2500" target="_blank">gasoline</a> powertrain options, the Sierra 2500 has immense towing and hauling capacity. The 2500 has well-mannered on-road handling and is equally at home on a dirt ranch road.  The configurations with the Sierra 2500 are nearly endless, with multiple cab sizes, bed lengths, and an array of powertrain choices. Some of the popular Sierra 2500 trims include the <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/at4" target="_blank">AT4</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali" target="_blank">Denali</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/denali-ultimate" target="_blank">Denali Ultimate</a>, <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/sle" target="_blank">SLE</a>, and <a href="https://www.autotrader.com/cars-for-sale/gmc/sierra-2500/slt" target="_blank">SLT</a>. Even with fierce competition in the heavy-duty pickup segment, the GMC Sierra 2500 still makes waves. With powerful towing capabilities, a luxurious interior, and refined on-road driving, the Sierra 2500 is a rewarding heavy-duty truck.  

Used GMC Sierra 2500 for Sale Under $30,000

Used GMC Sierra 2500 for Sale Under $20,000

Used GMC Sierra 2500 for Sale Under $15,000

Used GMC Sierra 2500 for Sale Under $5,000

Used GMC Sierra 2500 for Sale Under $25,000

Used GMC Sierra 2500 for Sale Under $10,000

Search from 110 GMC Sierra 2500 for sale, including a Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, a Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, and a Used 2016 GMC Sierra 2500 Denali ranging in price from $16,977 to $91,960.

Autotrader has 110 GMC Sierra 2500 for sale near O Fallon, MO, including a Certified 2022 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, a Certified 2024 GMC Sierra 2500 AT4 w/ AT4 Premium Plus Package, and a Used 2016 GMC Sierra 2500 Denali ranging in price from $16,977 to $91,960.

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Used GMC Sierra 2500 for Sale in O Fallon, MO

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Used 2023 GMC Sierra 2500 AT4 w/ AT4 Preferred Package

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